ANXA2

Annexin A2

as Docking Receptor

( Power by: MEGADOCK & IID. For better experience, use UCSF ChimeraX to visualize '.pdb' files. )

Database Statistics

Set	Unique Top Docking models
Complete Set	20503
IID Subset	509

Complete Set of docking models: ANXA2 (receptor) / AlphaFold (v.2) Human Proteins (ligand).

IID Subset Docking models: ANXA2 (receptor) / AlphaFold (v.2) Human (ligand) - of Proteins annotated at IID database.

Acknowledgments:

Molecular Docking performed with MEGADOCK, developed by Akiyama Laboratory, Tokyo Institute of Technology, Japan
Masahito Ohue, Takehiro Shimoda, Shuji Suzuki, Yuri Matsuzaki, Takashi Ishida, Yutaka Akiyama. MEGADOCK 4.0: an ultra-high-performance protein-protein docking software for heterogeneous supercomputers , Bioinformatics, 30(22): 3281-3283, 2014.

Molecular graphics and analyses performed with UCSF ChimeraX, developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco, with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.
UCSF ChimeraX: Tools for structure building and analysis. Meng EC, Goddard TD, Pettersen EF, Couch GS, Pearson ZJ, Morris JH, Ferrin TE. Protein Sci. 2023 Nov;32(11):e4792.
Proteins predicted structures (pdb-files) were obtained at AlphaFold Protein Stucture Database - developed by DeepMind, a subsidiary of Alphabet and EMBL-EBI.
Highly accurate protein structure prediction with AlphaFold. Jumper, J et al. Nature (2021).
AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences. Varadi, M et al. Nucleic Acids Research (2024).
Tissue specific PPI networks data was obtained at Integrated Interaction Database (IID) - database of detected and predicted protein-protein interactions (PPIs) developed by Jurisica Lab, Krembil Research Institute, Toronto, ON. Canada.
IID 2021: Towards context-specific protein interaction analyses by increased coverage, enhanced annotation and enrichment analysis. Kotlyar M, Pastrello C, Ahmed Z, Chee J, Varyova Z, Jurisica I. Nucl Acids Res, 50(D1):D640-D647, 2022.

Older web pages are still available here.

Jurisica Lab, Krembil Research Institute, Toronto, ON February 12, 2025 (Web: 1.0.1.1 / Database: 1.0.1.0)