Rec: Annexin A2 / Lig: Vimentin
Platform: AlphaFold Server
Data from: PDB Database


  1. The AlphaFold Server takes input at 'fasta format.
  2. Uniprot Database.
    • P07355 (ANXA2_HUMAN, Annexin A2) length is 339AA and that PDB Bank ID = 1W7B has complete ANXA2_HUMAN fasta structure,

      MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD

    • P08670 (VIME_HUMAN, Vimentin) length is 466 AA and that PDB Bank ID = 8RVE has complete VIME_HUMAN fasta structure.

      MSTRSVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE

  3. Log into AlphaFold Server, create and submit the job.
  4. In 3-10 minutes, the results will be ready.
  5. Here the summary looks like:
  6. AlphaFold Server provides output of 5 models (model# 0, 1, 2, 3, 4):


    model 0


    model 1


    model 2


    model 3


    model 4

    Download results


Jurisica Lab, Krembil Research Institute, Toronto, ON    February 12, 2025    (Web: 1.0.1.1