Below is Molecular Docking modeling of Q5QGZ9-Q9UMR7 protein pairs.
You can use this page:
- Download Top Model and / or Bio Model.
Top Model is the most probable docking pose of these 2 proteins from Molecular Mechanics point
of view but we also suggest trying a Bio Model if available.
Both Top Model and Bio Model computed under usual constraints including a rigid protein to protein docking.
Structurally, the Bio Model is quite similar to the Top Model but may be more prone for signaling as the
result of these proteins' interaction. You can deploy either of the models for further
Molecular Dynamics Computations.
- Use Contacts tables (at the next linked pages) for residues / atoms involved in structural contacts and probability of signaling.
Docked by MEGADOCK | |||||||
|---|---|---|---|---|---|---|---|
| Num | ID | Receptor click to download | Ligand click to download | Top position click to download | Best Bio position click to download | Top image Receptor: w Ligand: w BIO-score | Best Bio image Receptor: w Ligand: w RMSD to 'Top' / BIO-score |
| 1 | Q5QGZ9 - Q9UMR7 | Q5QGZ9 | Q9UMR7 | 1 | 3 |  24 Video Contacts |  0.85 / 68 Video Contacts |
| 2 | Q9UMR7 - Q5QGZ9 | Q9UMR7 | Q5QGZ9 | 1 | 1 |  8 Video Contacts | 0.00 / 8 Video Contacts |
- Click link in the Receptor column to download a pdb-file of protein which was used at a receptor (frozen in space) role in this docking modeling.
- Click link in the Ligand column to download a pdb-file of protein with ligand role in modeling.
- Click link in the Top position column to download the Top Model pdb-file.
- Click link in the Best Bio position column to download the Bio Model pdb-file.
- Below the image in the Top image column: Bio Score of the Top Model / URL link to Contacts tables for Top Model.
- Below the image in the Best Bio image column: The RMSD of Bio Model relative to the Top Model / Bio Score of the Bio Model / URL link to Contacts tables for Bio Model.
Note: Bio Score is a count of contacts when both receptor and ligand atoms are either in Alpha Helix or Beta Sheets. Higher Bio Score may lead to a greater probability of signaling. Bio Model would be a complex with the highest Bio Score in a Top Mode vicinity (RMSD <1), if its Bio Score surpasses the Top Model one. Otherwise, the Top Model is already a Bio Model.
Note: We recommend ChimeraX for pdb-files visualization.